aGEM that stands for “anatomic Gene Expresssion Mapping (aGEM)” is a development conceived to integrate phenotypic information from spatial and temporal distribution of expressed genes in human and mouse.
The aGEM Platform provides information to answer three main questions (1) Which are the genes that are expressed in a given anatomical component?, (2) in which anatomical structures a given gene (or set of genes) is expressed?, and (3) is there any correlation among these findings?. Currently this Platform includes several well-known mouse gene expression resources such as EMAGE, GXD, GENSAT, BioGPS, ABA, EUREXPRESS and three human gene expression databases: HUDSEN, BioGPS and Human Protein Atlas. Moreover, general biological information from databases such as KEGG, OMIM and MTB is integrated too. aGEM not only gives an integrated view of the eight databases mentioned above, but also allows the experimentalist to retrieve relevant statistical information relating gene expression, anatomical structure (space) and developmental stage (time).
Summarizing, aGEM Platform v3.1 is a powerful tool in the gene expression field that makes easy the access to information related to the anatomical pattern of gene expression in human and mouse, so that it can complement many functional genomics studies. The platform allows the integration of gene expression data with spatial-temporal anatomic data by means of an intuitive and user friendly display.